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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T22988 | MK-4827 Racemate | Niraparib Racemate,2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide | PARP |
MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1. | |||
T6892 | Niraparib tosylate | MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate | Apoptosis , PARP |
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor. | |||
T3353 | Niraparib hydrochloride | MK-4827 hydrochloride,MK-4827 (hydrochloride) | Apoptosis , Others , PARP |
Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of... | |||
T12064 | Niraparib (R-enantiomer) | MK 4827 (R-enantiomer),Niraparib R-enantiomer | PARP |
Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM). |